Gram-Negative Bacteria: The cell Membranes

Cell Envelope Structure and Functions in Gram-negative Bacteria

Lipid membrane-binding properties of daptomycin using surface plasmon resonance.

In the present study, we developed an assay of interactions of daptomycin with four model lipid membranes that mimicked mammal cell membranes and gram-positive and negative bacteria membranes. We also analyzed the binding kinetics of the gram-positive bacteria membranes using surface plasmon resonance (SPR). Daptomycin showed a higher affinity for the model gram-positive bacteria membrane than ...

Classic Spotlight: Gram-Negative Bacteria Have Two Membranes.

The Danish microbiologist Hans Christian Gram developed a staining technique (1884) that classifies most bacteria into two large groups that are referred to eponymously, as Gram-positive and Gram-negative bacteria (1). His stain is still used in medical microbiology labs today, and because of its explanatory power, this classification is the most commonly used descriptor of a particular bacteri...

Gram-Negative Bacteria: The cell Membranes

This chapter presents a brief outline of our current knowledge of the structures of the bounding membranes (the inner and the outer membranes and the intermediate periplasmic layer) of a Gram-negative bacterial cell. Also the structure and chemical composition of the outer membrane vesicles (OMVs) originating from the surface of these bacteria including their proteomic profile, as obtained main...

Oligopolyphenylenevinylene-conjugated oligoelectrolyte membrane insertion molecules selectively disrupt cell envelopes of Gram-positive bacteria.

The modification of microbial membranes to achieve biotechnological strain improvement with exogenous small molecules, such as oligopolyphenylenevinylene-conjugated oligoelectrolyte (OPV-COE) membrane insertion molecules (MIMs), is an emerging biotechnological field. Little is known about the interactions of OPV-COEs with their target, the bacterial envelope. We studied the toxicity of three pr...